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Hematology & Oncology


The medical field of hematology is concerned with both benign and malignant forms of blood diseases while the field of oncology is concerned with cancer. AOP Orphan has taken a particular interest in myeloproliferative disorders. This group of disorders of the bone marrow is characterized by the autonomous proliferation of blood progenitor cells.

Chemotherapy-Induced Nausea and Vomiting (CINV)

Many essential cytostatic agents often cause vomiting and nausea. For this reason, most patients are usually given medication to avoid or prevent such serious side effects before undergoing emetogenic chemotherapy.

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Essential thrombocythemia

Essential thrombocythemia is a disorder of the bone marrow characterized by a clear overproduction of platelets (thrombocytes). This overproduction of platelets can lead to an increased risk of blood clots (thrombus) and bleeding (hemorrhage).

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Polycythemia vera

Polycythemia vera (PV) is a Rare Disease of the blood-building cells in the bone marrow primarily resulting in a chronic increase of red blood cells (erythrocytes), thereby decreasing the flowability of blood.

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Primary myelofibrosis

Primary myelofibrosis is a disorder of the bone marrow and is currently classified as a myeloproliferative disease in which the proliferation of an abnormal type of bone marrow stem cell results in fibrosis or the replacement of the marrow with collagenous connective tissue.

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Chronic myelogenous leukemia

Chronic myelogenous leukemia (CML) is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood.

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